2025-10-13
Core vegan raw materials for joint and bone health have achieved efficient nutrient supply without animal components through microbial fermentation, plant extraction, and biosynthesis technologies. The following are the core vegan raw materials for joint and bone health that are currently widely used in the market:
1. Raw Materials for Joint Structure Repair and Lubrication
(1)Vegan Glucosamine
Core Source: Produced via microbial fermentation, completely avoiding extraction from animal sources such as shrimp and crab shells. It poses no seafood allergy risk and is compliant with vegetarian and vegan standards.
Core Efficacy: As a key precursor for the synthesis of glycosaminoglycans (GAGs, the critical structural component of articular cartilage) in the cartilage matrix, it directly provides "raw materials" for chondrocytes, promotes chondrocyte proliferation and matrix regeneration, helps repair damaged cartilage tissue, and maintains cartilage elasticity and toughness.
Scientific Support and Usage Recommendations: Clinically, it is often used in combination with chondroitin-based ingredients to enhance cartilage repair efficiency. The regular daily recommended dosage is 1500mg, and it is suitable for various end formulations such as capsules and tablets.
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Vegan Glucosamine Sulfate 2NACL Glucosamine Sulfate Potassium Chloride
(2). Vegan Chondroitin Sulfate – Represented by Plondroitin®,Plondroitin® is a vegan chondroitin sulfate-based raw material developed by HS Nutra Co., Ltd.
Extraction Source: Bioactive polysaccharides extracted from marine algae, a 100% plant-based source that avoids disputes related to animal ethics and environmental protection.
Core Advantages:
Structural Compatibility: Verified by Fourier Transform Infrared Spectroscopy (FTIR), its glycosaminoglycan structure is highly consistent with traditional shark-derived chondroitin sulfate, enabling precise supplementation of key components required for cartilage structure.
High Active Content: The content of core active ingredient (glycosaminoglycans, calculated as CS) is ≥90%. It is also rich in uronic acid and organic sulfate groups, which can promote cartilage matrix synthesis and delay cartilage degradation.
Usage Recommendations: The daily recommended dosage is 200-400mg. It can be used alone or combined with vegetarian glucosamine to enhance cartilage repair effects.
(3). Vegan Hyaluronic Acid (HA)
Core Source: Produced by microbial fermentation of Streptococcus and other microorganisms, replacing traditional animal-derived extraction methods and meeting vegetarian standards.
Core Efficacy: As the main component of synovial fluid, it can significantly improve the viscosity and lubricity of synovial fluid, reducing friction-induced damage to joint surfaces. Meanwhile, it forms a protective film on the cartilage surface, inhibits the erosion of inflammatory factors on cartilage, alleviates joint stiffness, and improves joint mobility.
Scientific Support and Usage Recommendations: Clinical studies have shown that daily supplementation of 80-120mg can effectively enhance the quality of synovial fluid. It is suitable for formulations such as liquids, gummies, and capsules, and is particularly suitable for people with dry joints and limited mobility.
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2. Raw Materials for Anti-Inflammation and Antioxidation
Core Source: Extracted and purified from the rhizomes of Curcuma longa (a Zingiberaceae plant), it is of natural plant origin with no association with animal components.
Core Efficacy: By inhibiting the NF-κB (nuclear factor kappa B) inflammatory signaling pathway, it reduces the release of pro-inflammatory factors (e.g., TNF-α, IL-6) and decreases the activity of cartilage-degrading enzymes (matrix metalloproteinases, MMPs). This dual action blocks the "inflammation-cartilage damage" vicious cycle and alleviates joint swelling and pain.
Scientific Support and Usage Recommendations: Human experimental data show that daily supplementation of 300mg curcumin can reduce pain scores by 25%-30% in patients with osteoarthritis. Due to its low bioavailability, it is often combined with black pepper extract (piperine) to improve absorption efficiency.
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(2). Methylsulfonylmethane (MSM)
Core Source: Naturally present in cruciferous vegetables (e.g., broccoli, cabbage), and can also be produced via vegetarian-friendly chemical synthesis processes, with no animal-derived ingredients involved in the entire process.
Core Efficacy:
Anti-Inflammatory and Analgesic: Supplements sulfur, an essential element for cartilage tissue, and inhibits the release of inflammatory mediators to alleviate chronic joint pain.
Synergistic Protection: When combined with ingredients such as curcumin and vegetarian glucosamine, it enhances the synergistic effect of anti-inflammation and cartilage repair, improving joint mobility and flexibility.
Scientific Support and Usage Recommendations: Clinical studies indicate that daily supplementation of 1-3g MSM can significantly improve joint mobility in patients with osteoarthritis and reduce the frequency of pain episodes. It is suitable for formulations such as tablets, capsules, and solid beverages.
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About Us
HS Nutra Co., Ltd. was formerly known as Jiaxing Hengjie Biopharmaceutical Co., Ltd., founded in 2001, and renamed in 2024. It is a national-level high-tech enterprise focused on raw materials for joint and bone health and dietary supplements, with its headquarters in Jiaxing, Zhejiang, and its factory covering an area of over 20,000 square meters.
It is one of the early enterprises in China to lay out chondroitin sulfate sodium series products. Its core products include chondroitin sulfate sodium, glucosamine, collagen, and hyaluronic acid, along with vegetarian-sourced raw materials such as Plondroitin®. Its quality meets the pharmacopoeia standards of multiple countries, including the Chinese Pharmacopoeia (CP) and the United States Pharmacopeia (USP), with customizable parameters.
The company has a Grade D GMP workshop and a self-built QC laboratory, and has obtained certifications including NSF-GMP, ISO 9001, and ISO 22000. It has built a full-lifecycle R&D ecosystem and undertaken scientific research projects such as the Innovation Fund of the Ministry of Science and Technology of China. Its products are sold to 18 buyers worldwide, with key markets including India and the United States. It cooperates with international dietary supplement enterprises and enjoys a good reputation.
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